Glybenzcyclamide 10238-21-8

1.Glybenzcyclamide 2.White crystalline powder 3.Professional manufacture 4.High quality competitive price

Description 

Name	glyburide
Appearance	White crystalline powder
Cas	10238-21-8
MF	C23H22ClN3O5S
Mol. mass	487.9559
Grade	Medicine grade
Assay	99.6%
Density	1.376g/cm3
EINECS	233-570-6
Usage	Hypoglycemic
Delivery	1 to 3 days
Package	1kg/Aluminum foil bag,25kg/drum

  

  Medical uses 

Glybenzcyclamide (INN), also known as glyburide (USAN), a second-generation sulfonylurea antidiabetic agent, appears to lower the blood glucose acutely by stimulating the release of insulin from the pancreas, an effect dependent upon functioning beta cells in the pancreatic islets. With chronic administration in Type II diabetic patients, the blood glucose lowering effect persists despite a gradual decline in the insulin secretory response to the drug. Extrapancreatic effects may be involved in the mechanism of action of oral sulfonyl-urea hypoglycemic drugs. The combination of glibenclamide and metformin may have a synergistic effect, since both agents act to improve glucose tolerance by different but complementary mechanisms. In addition to its blood glucose lowering actions, glibenclamide produces a mild diuresis by enhancement of renal free water clearance. Glybenzcyclamide is twice as potent as the related second-generation agent glipizide.

   Contact information

Gary Ren

Zhengzhou Debao Fine Chemical co., ltd

Phone: 86 150 3800 2977

Tel: 86 371 69123168

  

Glybenzcyclamide 10238-21-8